BDBM50166948 CHEMBL3799255

SMILES COc1cc(ccc1Nc1ncc(SC)c(Oc2cccc(NC(=O)C=C)c2)n1)N1CCN(CC1)C(=O)C(F)(F)F

InChI Key InChIKey=LYCJWVRLAGIQEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166948   

TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166948(CHEMBL3799255)
Affinity DataIC50: 248nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50166948(CHEMBL3799255)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed