BDBM50166894 6-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-chromen-4-one::CHEMBL424829::US8552057, 10

SMILES COc1cc(ccc1O)-c1cc(=O)c2cc(O)ccc2o1

InChI Key InChIKey=KKRDHOHXRPHWRL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50166894   

TargetEstrogen receptor beta(Human)
University of Southern California

US Patent
LigandPNGBDBM50166894(CHEMBL424829 | US8552057, 10 | 6-Hydroxy-2-(4-hydr...)
Affinity DataIC50: 4.48E+3nMAssay Description:The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2013
Entry Details
Go to US Patent

TargetEstrogen receptor beta(Human)
University of Southern California

US Patent
LigandPNGBDBM50166894(CHEMBL424829 | US8552057, 10 | 6-Hydroxy-2-(4-hydr...)
Affinity DataIC50: 4.48E+3nMAssay Description:Binding affinity for human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Southern California

US Patent
LigandPNGBDBM50166894(CHEMBL424829 | US8552057, 10 | 6-Hydroxy-2-(4-hydr...)
Affinity DataIC50: 4.48E+3nMAssay Description:Binding affinity for human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50166894(CHEMBL424829 | US8552057, 10 | 6-Hydroxy-2-(4-hydr...)
Affinity DataIC50: 1.70E+6nMAssay Description:Displacement of EL red from human full-length ER-alpha expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Southern California

US Patent
LigandPNGBDBM50166894(CHEMBL424829 | US8552057, 10 | 6-Hydroxy-2-(4-hydr...)
Affinity DataIC50: 58nMAssay Description:Displacement of EL red from human full-length ER-beta expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed