BDBM50166886 CHEMBL195368::methyl alpha-D-mannoside

SMILES CO[C@@H]1[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

InChI Key InChIKey=HOVAGTYPODGVJG-UHFFFAOYSA-N

Data  8 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50166886   

TargetConcanavalin-A(Jack bean)
Georgia Southern University

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetType 1 fimbrin D-mannose specific adhesin(Escherichia coli (strain K12))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at Escherichia coli recombinant C-terminal 6His-tagged FimH-CRD with a C-terminal thrombin cleavage site expressed in Escherichia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 3.70E+4nMAssay Description:Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetC-type lectin domain family 4 member M(Human)
University of Picardy Jules Verne

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 1.27E+6nMAssay Description:Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 4.68E+4nMAssay Description:Competitive binding affinity to recombinant Pseudomonas aeruginosa PA14 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetFucose-binding lectin PA-IIL(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataIC50: 1.04E+5nMAssay Description:Competitive binding affinity to recombinant Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Indian Institute of Technology Bombay

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataKd:  71nMAssay Description:Binding affinity to recombinant Pseudomonas aeruginosa LecA expressed in Escherichia coli BL21 (DE3) expression system assessed as dissociation const...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetType 1 fimbrin D-mannose specific adhesin(Escherichia coli (strain K12))
University of Basel

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to Escherichia coli FimH assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPA-I galactophilic lectin(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Indian Institute of Technology Bombay

Curated by ChEMBL
LigandPNGBDBM50166886(methyl alpha-D-mannoside | CHEMBL195368)
Affinity DataKd:  7.10E+4nMAssay Description:Binding affinity to Pseudomonas aeruginosa PAO1 LecA assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed