BDBM50166873 CHEMBL3800456

SMILES Cc1ccccc1OC(=O)N1CCC(CC1)c1nc(cs1)C1=NOC(C1)c1ccccc1

InChI Key InChIKey=MTEFYFBFEAYANN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166873   

TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166873(CHEMBL3800456)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetLiver carboxylesterase(Pig)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166873(CHEMBL3800456)
Affinity DataIC50: 840nMAssay Description:Inhibition of porcine liver esterase using 4-nitrophenyl butyrate substrate assessed as reduction in p-nitrophenol release measured over 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
E.I. Du Pont De Nemours

Curated by ChEMBL
LigandPNGBDBM50166873(CHEMBL3800456)
Affinity DataKi:  0.00300nMAssay Description:Inhibition of MBP-fused human recombinant FAAH with truncated N-terminal transmembrane domain expressed in Escherichia coli T7 using D-AMC substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed