BDBM50166628 CHEMBL189430::N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-ethyl]-2-[4-(2-methanesulfonylamino-ethyl)-phenyl]-N-methyl-acetamide

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)Cc1ccc(CCNS(C)(=O)=O)cc1

InChI Key InChIKey=KTAVXLZYDREVGZ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166628   

TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50166628(N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-...)
Affinity DataEC50:  17nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50166628(N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-...)
Affinity DataKi:  2.80nMAssay Description:Inhibitory constant against human Opioid receptor kappa using [3H]-diprenorphine as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50166628(N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-...)
Affinity DataKi:  107nMAssay Description:Inhibitory constant against human Opioid receptor delta 1 using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50166628(N-[(S)-2-((S)-3-Hydroxy-pyrrolidin-1-yl)-1-phenyl-...)
Affinity DataKi:  785nMAssay Description:Inhibitory constant against human Opioid receptor mu 1 using [3H]diprenorphine as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed