BDBM50166611 CHEMBL3800352

SMILES COc1cc(CCc2cc(Nc3ncnc4cc(NCCN5CCOCC5)ccc34)n[nH]2)cc(OC)c1

InChI Key InChIKey=RRUKQYUSSNTAOJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166611   

TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166611(CHEMBL3800352)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166611(CHEMBL3800352)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50166611(CHEMBL3800352)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed