BDBM50166576 CHEMBL3799257

SMILES Cn1ncc2cc(ccc12)C(=O)Nc1nnc(s1)C1CC1

InChI Key InChIKey=NLBFOTBSUFNAJN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166576   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166576(CHEMBL3799257)
Affinity DataIC50: 6.70E+3nMAssay Description:Antagonist activity at human recombinant EP3 receptor expressed in CHOK1 cells assessed as inhibition of sulprostone-induced decrease in cAMP level p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166576(CHEMBL3799257)
Affinity DataKi:  5.89E+3nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in human Chem1 cell membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed