BDBM50166574 CHEMBL3798598

SMILES CCN1CCOc2ccc(cc12)C(=O)Nc1nnc(s1)C1CC1

InChI Key InChIKey=HLWKISDEYFIAEV-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50166574   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166574(CHEMBL3798598)
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human recombinant EP3 receptor expressed in CHOK1 cells assessed as inhibition of sulprostone-induced decrease in cAMP level p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166574(CHEMBL3798598)
Affinity DataKi:  77nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP3 receptor expressed in human Chem1 cell membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166574(CHEMBL3798598)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in human Chem1 cell membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166574(CHEMBL3798598)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in human Chem1 cell membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50166574(CHEMBL3798598)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP4 receptor expressed in human Chem1 cell membrane by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed