BDBM50166281 CHEMBL192789::[5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-yl]-acetic acid ethyl ester::ethyl 2-(2-methyl-5-(4-(methylsulfonyl)phenyl)-1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)acetate

SMILES CCOC(=O)Cc1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ZKJFNNNFBXEDAX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50166281   

TargetProstaglandin G/H synthase 1(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166281([5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-triflu...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in murine J774 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166281([5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-triflu...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 in murine J774 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166281([5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-triflu...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse COX2 in LPS-stimulated mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166281([5-(4-Methanesulfonyl-phenyl)-2-methyl-1-(4-triflu...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse COX1 in mouse J774 cells assessed as PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed