BDBM50166049 (1S,2R)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)cyclohexanecarboxamide::2-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino]-cyclohexanecarboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL365583

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCC[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=ZWSMYALLYGLVNZ-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50166049   

TargetMu-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166049(2-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino...)
Affinity DataEC50:  569nMAssay Description:Activity at mu opioid receptor in Wistar rat brain assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166049(2-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of endomorphin-2 binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166049(2-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino...)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166049(2-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50166049(2-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylamino...)
Affinity DataKi:  812nMAssay Description:Displacement of [3H]Ile5,6deltorphin-2 from delta opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed