BDBM50166034 1-(2,4-Dihydroxy-phenyl)-2-(4-hydroxy-phenyl)-ethanone::2,4,4'-Trihydroxydeoxybenzoin::2,4,4'-terthydroxydeoxybenzoin::CHEMBL193200::US20240398793, Compound 10

SMILES Oc1ccc(CC(=O)c2ccc(O)cc2O)cc1

InChI Key InChIKey=KLFCJXAPIFIIFR-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50166034   

TargetSex hormone-binding globulin(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataIC50: 1.72E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 150 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 90 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of mushroom tyrosinase activity after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human estrogen receptor-beta by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataEC50:  2.03E+3nMAssay Description:Agonist activity at human estrogen receptor-alpha by yeast two-hybrid assay in presence of SRC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Celltaxis

US Patent
LigandPNGBDBM50166034(2,4,4'-terthydroxydeoxybenzoin | 2,4,4'-Trihydroxy...)
Affinity DataIC50: 3.42E+4nMAssay Description:The hydrolase-homogeneous time resolved fluorescence assay is a two-step assay that measures the hydrolysis of LTA4 to LTB4 by analyzing the amount o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent