BDBM50165972 CHEMBL3800348

SMILES COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=PZSVADNOJUBASZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165972   

TargetVascular endothelial growth factor receptor 2(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50165972(CHEMBL3800348)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in IL3 deficient BAF3 cells assessed as reduction in cell viability after 48 hrs by CellTite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50165972(CHEMBL3800348)
Affinity DataIC50: 29nMAssay Description:Inhibition of N-terminal GST fused human RET (658 to 1114 amino acid residue) using CSKtide as substrate expressed in baculovirus preincubated for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2017
Entry Details Article
PubMed
LigandPNGBDBM50165972(CHEMBL3800348)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant KIF5B/RET (unknown origin) expressed in IL3 deficient BAF3 cells assessed as reduction in cell viability after 48 hrs by Ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2017
Entry Details Article
PubMed