BDBM50165934 Ac-YR[CE(1-Me-H)dFRWC]-NH2::CHEMBL264132

SMILES CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cncn2C)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O

InChI Key InChIKey=JCRBBWBYSVHLIT-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50165934   

TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165934(Ac-YR[CE(1-Me-H)dFRWC]-NH2 | CHEMBL264132)
Affinity DataEC50:  0.540nMAssay Description:Agonist activity at human Melanocortin-4 receptor as peptide required for 50% maximal cAMP release (n > or =2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165934(Ac-YR[CE(1-Me-H)dFRWC]-NH2 | CHEMBL264132)
Affinity DataKi:  6.60nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165934(Ac-YR[CE(1-Me-H)dFRWC]-NH2 | CHEMBL264132)
Affinity DataKi: >500nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165934(Ac-YR[CE(1-Me-H)dFRWC]-NH2 | CHEMBL264132)
Affinity DataKi: >500nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165934(Ac-YR[CE(1-Me-H)dFRWC]-NH2 | CHEMBL264132)
Affinity DataKi: >500nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed