BDBM501657 US11028054, Example 52

SMILES Cc1nc2c(cc(cc2[nH]1)-c1c(F)c(F)c(-c2ccccc2)c(F)c1F)C(O)=O

InChI Key InChIKey=HNOVWEWVRXDXCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 501657   

LigandPNGBDBM501657(US11028054, Example 52)
Affinity DataIC50: 5.5nMAssay Description:Reagents used: L-Dihydroorotic acid, Sigma, D7128, 2,6-Dichloroindophenol sodium salt hydrate, sigma, D1878 Dimethyl sulfoxide (DMSO), spectroscopic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
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LigandPNGBDBM501657(US11028054, Example 52)
Affinity DataIC50: 1nMAssay Description:Inhibition of DHODH (unknown origin) using L-dihydroorotic acid as substrate preincubated for 30 mins followed by substrate addition measured every 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed