BDBM50165671 CHEMBL196647::N-{(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-3-hydroxycarbamoyl-propyl}-N'-[3-[(biphenyl-4-sulfonyl)-isopropoxy-amino]-3-((R)-hydroxycarbamoyl)-propyl]-isophthalamide

SMILES CC(C)ON([C@H](CCNC(=O)c1cccc(c1)C(=O)NCC[C@@H](N(OC(C)C)S(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YZYVVJVNDAWVKA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50165671   

Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50165671(N-{(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-...)
Affinity DataIC50: 197nMAssay Description:Inhibition of Matrix metalloprotease-2 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50165671(N-{(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-...)
Affinity DataIC50: 983nMAssay Description:Inhibition of Matrix metalloprotease-9 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50165671(N-{(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-...)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of Matrix metalloprotease-14 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50165671(N-{(R)-3-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1 in MMPi assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed