BDBM50165598 CHEMBL3797857

SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)[C@@H](Cc2ccccc2)NC=O)cc1

InChI Key InChIKey=DVBPDCTXXKIINT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165598   

TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50165598(CHEMBL3797857)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50165598(CHEMBL3797857)
Affinity DataKi:  59nMAssay Description:Displacement of [125I]-His9-ghrelin from human GHS-R1a transfected in pig LLC PK-1 cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50165598(CHEMBL3797857)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2017
Entry Details Article
PubMed