BDBM50165466 CHEMBL3800420

SMILES Cn1cc(cn1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1

InChI Key InChIKey=ACOJXRCLGVKBMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165466   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165466(CHEMBL3800420)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165466(CHEMBL3800420)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2017
Entry Details Article
PubMed