BDBM50165454 4-(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-ylsulfanyl)-benzonitrile::CHEMBL195867

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(cc1)C#N

InChI Key InChIKey=MUGHEODXAJBTPA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165454   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165454(4-(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2...)
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165454(4-(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibitory concentration against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165454(4-(2-Amino-6-methyl-4-oxo-4,7-dihydro-3H-pyrrolo[2...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibitory concentration against human dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed