BDBM50165438 2-Amino-6-methyl-5-(4-trifluoromethyl-phenylsulfanyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL364453

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HYBYGJYSGVUEQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165438   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165438(2-Amino-6-methyl-5-(4-trifluoromethyl-phenylsulfan...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory concentration against human dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165438(2-Amino-6-methyl-5-(4-trifluoromethyl-phenylsulfan...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165438(2-Amino-6-methyl-5-(4-trifluoromethyl-phenylsulfan...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory concentration against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed