BDBM50165428 CHEMBL196240::[(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-indan-1-yl ester

SMILES CCCC[C@H](NC(=O)O[C@H]1CCc2ccccc12)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=DQSSVNLGIWUXRQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50165428   

TargetPro-cathepsin H(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165428([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against human cathepsin H by fluorescence assay using 50 uM L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165428([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 460nMAssay Description:Inhibitory concentration against human cathepsin L by fluorescence assay using 5 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165428([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165428([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against human cathepsin B by fluorescence assay using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165428([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration against human cathepsin V by fluorescence assay using 2 uM Cbz-Phe-Arg-AMC More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165428([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against human cathepsin S by fluorescence assay using 10 uM Cbz-Val-Val-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed