BDBM50165342 CHEMBL193356::hydrogen 1-hydroxy-2-(3-methylpyridinium-1-yl)-1-phosphonoethylphosphonate

SMILES Cc1ccc[n+](CC(O)(P(O)(O)=O)P(O)([O-])=O)c1

InChI Key InChIKey=WNMNDCTVXVBAFC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165342   

Target4-hydroxy-3-methylbut-2-enyl diphosphate reductase(Aquifex aeolicus (strain VF5))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50165342(hydrogen 1-hydroxy-2-(3-methylpyridinium-1-yl)-1-p...)
Affinity DataIC50: 5.40E+5nMAssay Description:Inhibition of Aquifex aeolicus IspH expressed in Escherichia coli BL21 (DE3) using HMBPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50165342(hydrogen 1-hydroxy-2-(3-methylpyridinium-1-yl)-1-p...)
Affinity DataKi:  38nMAssay Description:Binding affinity towards Farnesyl diphosphate synthase from leishmania majorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed