BDBM50165307 9-Pent-4-ynyl-8-(4-pyrrol-1-yl-phenylsulfanyl)-9H-purin-6-ylamine::CHEMBL364730

SMILES Nc1ncnc2n(CCCC#C)c(Sc3ccc(cc3)-n3cccc3)nc12

InChI Key InChIKey=CWGISTTUWFSZCN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165307   

TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165307(9-Pent-4-ynyl-8-(4-pyrrol-1-yl-phenylsulfanyl)-9H-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165307(9-Pent-4-ynyl-8-(4-pyrrol-1-yl-phenylsulfanyl)-9H-...)
Affinity DataIC50: 3.11E+5nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed