BDBM50165056 6-Furan-2-yl-9-(4-trifluoromethyl-benzyl)-9H-purin-2-ylamine::9-(4-(trifluoromethyl)benzyl)-6-(furan-2-yl)-9H-purin-2-amine::CHEMBL424827

SMILES Nc1nc(-c2ccco2)c2ncn(Cc3ccc(cc3)C(F)(F)F)c2n1

InChI Key InChIKey=LSFHXSDZJHMJAH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165056   

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50165056(9-(4-(trifluoromethyl)benzyl)-6-(furan-2-yl)-9H-pu...)
Affinity DataKi:  6nMAssay Description:Binding affinity at human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50165056(9-(4-(trifluoromethyl)benzyl)-6-(furan-2-yl)-9H-pu...)
Affinity DataKi:  20.5nMAssay Description:Inhibition constant against human Adenosine A2a receptor using [3H]-SCH- 58261 as radioligand expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50165056(9-(4-(trifluoromethyl)benzyl)-6-(furan-2-yl)-9H-pu...)
Affinity DataKi:  3.29E+3nMAssay Description:Binding affinity at human adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed