BDBM50165031 6-({3-isopropoxy-5-[2-(3-thienyl)ethoxy]benzoyl}amino)nicotinic acid::6-[3-Isopropoxy-5-(2-thiophen-3-yl-ethoxy)-benzoylamino]-nicotinic acid::CHEMBL373339

SMILES CC(C)Oc1cc(OCCc2ccsc2)cc(c1)C(=O)Nc1ccc(cn1)C(O)=O

InChI Key InChIKey=PTEMBHHJYAKKNK-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165031   

TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50165031(6-[3-Isopropoxy-5-(2-thiophen-3-yl-ethoxy)-benzoyl...)
Affinity DataKd:  170nMAssay Description:Binding affinity to recombinant wild-type human pancreatic glucokinase expressed in Escherichia coli K-12 at 100 uM by isothermal titration calorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50165031(6-[3-Isopropoxy-5-(2-thiophen-3-yl-ethoxy)-benzoyl...)
Affinity DataEC50:  90nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Florida State University

Curated by ChEMBL
LigandPNGBDBM50165031(6-[3-Isopropoxy-5-(2-thiophen-3-yl-ethoxy)-benzoyl...)
Affinity DataEC50:  3.10E+3nMAssay Description:Activation of glucokinase (unknown origin) using glucose as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed