BDBM50165 (5Z)-3-benzyl-5-[(5-methyl-2-furyl)methylene]-2-thioxo-thiazolidin-4-one::(5Z)-3-benzyl-5-[(5-methylfuran-2-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-5-[(5-methyl-2-furanyl)methylidene]-3-(phenylmethyl)-2-sulfanylidene-4-thiazolidinone::(5Z)-5-[(5-methylfuran-2-yl)methylidene]-3-(phenylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one::3-benzyl-5-[(5-methyl-2-furyl)methylene]-2-thioxo-1,3-thiazolidin-4-one::MLS000575978::SMR000197009::cid_1328586

SMILES Cc1ccc(\C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1

InChI Key InChIKey=URBAPBDGZNYFGE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165   

LigandPNGBDBM50165(cid_1328586 | MLS000575978 | (5Z)-5-[(5-methylfura...)
Affinity DataIC50: 3.76E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
State Key Laboratory of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50165(cid_1328586 | MLS000575978 | (5Z)-5-[(5-methylfura...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged human DHODH (Met30 to Arg396) expressed in Escherichia coli BL21 (DE3) using dihydroorotate as substrate measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
State Key Laboratory of Bioreactor Engineering

Curated by ChEMBL
LigandPNGBDBM50165(cid_1328586 | MLS000575978 | (5Z)-5-[(5-methylfura...)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of Plasmodium falciparum DHODH (Phe158 to Ser569) expressed in Escherichia coli BL21 using dihydroorotate as substrate measured every 30 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed