BDBM50164959 (4-Bromo-phenyl)-carbamic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester::CHEMBL372419::US8541447, 4

SMILES Brc1ccc(NC(=O)OC2CN3CCC2CC3)cc1

InChI Key InChIKey=SLJMPDGIEKZJAU-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50164959   

LigandPNGBDBM50164959(US8541447, 4 | CHEMBL372419 | (4-Bromo-phenyl)-car...)
Affinity DataKi:  40nMAssay Description:Binding affinity to alpha7 nAChR in rat hippocampal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Targacept

US Patent
LigandPNGBDBM50164959(US8541447, 4 | CHEMBL372419 | (4-Bromo-phenyl)-car...)
Affinity DataKi:  40nMAssay Description:Binding assay using alpha 7 nAChR.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
Go to US Patent

LigandPNGBDBM50164959(US8541447, 4 | CHEMBL372419 | (4-Bromo-phenyl)-car...)
Affinity DataKi:  40nMAssay Description:Inhibitory constant against [3H]methyllycaconitine binding towards Nicotinic acetylcholine receptor alpha-7 of rat brain hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Targacept

US Patent
LigandPNGBDBM50164959(US8541447, 4 | CHEMBL372419 | (4-Bromo-phenyl)-car...)
Affinity DataKi:  167nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50164959(US8541447, 4 | CHEMBL372419 | (4-Bromo-phenyl)-car...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2; Not significantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed