BDBM50164770 CHEMBL3799275

SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc2ccccc2c1

InChI Key InChIKey=BHSUCGLRVZHATB-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164770   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164770(CHEMBL3799275)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant FLT3 expressed in insect cells using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE assay in presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164770(CHEMBL3799275)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant FLT4 using Ulight-CAGAGAIETDKEYYTVKD as substrate after 90 mins by LANCE assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Ontario Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50164770(CHEMBL3799275)
Affinity DataKd:  50nMAssay Description:Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2017
Entry Details Article
PubMed