BDBM50164618 (2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxazolidin]-2'-one::CHEMBL192704

SMILES Clc1ccc(s1)N1C[C@@]2(CN3CCC2CC3)OC1=O

InChI Key InChIKey=VEZBOQCTMXVJAG-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164618   

TargetCytochrome P450 2D6(Human)
Targacept

Curated by ChEMBL
LigandPNGBDBM50164618((2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Targacept

Curated by ChEMBL
LigandPNGBDBM50164618((2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50164618((2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataKi:  9nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164618((2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataKi:  9nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed