BDBM50164466 2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluoro-ethyl)-phenylamine::CHEMBL188964::N-(2-{[2-amino-4-(2-fluoroethyl)phenyl]thio}benzyl)-N,N-dimethylamine

SMILES CN(C)Cc1ccccc1Sc1ccc(CCF)cc1N

InChI Key InChIKey=LOONKLFFRKQSJD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50164466   

TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  1.83nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  8.5nMAssay Description:In vitro inhibition of [3H]citalopram binding to human serotonin transporter expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  946nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]WIN-35428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed