BDBM50164465 CHEMBL190937::N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine::[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-phenyl]-methanol

SMILES CN(C)Cc1ccccc1Sc1ccc(CO)cc1N

InChI Key InChIKey=IAGCXXVAWFKIDP-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50164465   

TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  0.570nMAssay Description:In vitro inhibition of [3H]citalopram binding to human serotonin transporter expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  0.800nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  303nMAssay Description:In vitro inhibition of [3H]nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  303nMAssay Description:Displacement of [3H]nisoxetine from human NET t expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  787nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]WIN-35428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  3.61E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed