BDBM50164396 CHEMBL3799103

SMILES CCN(Cc1cc(=O)n2c(C#N)c(C)sc2n1)c1ccc(F)cc1

InChI Key InChIKey=CCBWSWGULULTNH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164396   

TargetGlutamate receptor 2(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164396(CHEMBL3799103)
Affinity DataEC50:  6.66E+4nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flip isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164396(CHEMBL3799103)
Affinity DataEC50:  129nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164396(CHEMBL3799103)
Affinity DataEC50:  1.07E+4nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flop isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed