BDBM50164234 1-Cyclopentanesulfonyl-6-[2-(2,6-difluoro-phenyl)-5-phenyl-3H-imidazol-4-yl]-1H-benzoimidazol-2-ylamine; Bismesylate salt::CHEMBL193247

SMILES Nc1nc2ccc(cc2n1S(=O)(=O)C1CCCC1)-c1[nH]c(nc1-c1ccccc1)-c1c(F)cccc1F

InChI Key InChIKey=DMVLGJOBKSHMDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164234   

TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164234(1-Cyclopentanesulfonyl-6-[2-(2,6-difluoro-phenyl)-...)
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164234(1-Cyclopentanesulfonyl-6-[2-(2,6-difluoro-phenyl)-...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibitory concentration against Cytochrome P450 3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed