BDBM50164233 6-(2-(2,6-dichlorophenyl)-4-phenyl-1H-imidazol-5-yl)-1-(isopropylsulfonyl)-1H-benzo[d]imidazol-2-amine monomesylate::6-[2-(2,6-Dichloro-phenyl)-5-phenyl-3H-imidazol-4-yl]-1-(propane-2-sulfonyl)-1H-benzoimidazol-2-ylamine; compound with methanesulfonic acid::CHEMBL192889

SMILES CC(C)S(=O)(=O)n1c(N)nc2ccc(cc12)-c1nc([nH]c1-c1ccccc1)-c1c(Cl)cccc1Cl

InChI Key InChIKey=SMMQBPFFQVLHOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164233   

TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164233(6-[2-(2,6-Dichloro-phenyl)-5-phenyl-3H-imidazol-4-...)
Affinity DataIC50: 15.3nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164233(6-[2-(2,6-Dichloro-phenyl)-5-phenyl-3H-imidazol-4-...)
Affinity DataIC50: 15.3nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50164233(6-[2-(2,6-Dichloro-phenyl)-5-phenyl-3H-imidazol-4-...)
Affinity DataIC50: 38.9nMAssay Description:Inhibition of mouse p38alpha in anisomycin-stimulated RAW 264.7 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed