BDBM50164143 2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-dimethyl-phenyl)-5,8-dimethyl-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL180821

SMILES CCN(CC)CCOc1ccc(Nc2ncc3c(C)c(-c4c(C)cccc4C)c(=O)n(C)c3n2)cc1

InChI Key InChIKey=SCXAQLWEFWQGGR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164143   

TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50164143(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 540nMAssay Description:Inhibition of checkpoint kinase Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50164143(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 540nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164143(2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(2,6-d...)
Affinity DataIC50: 360nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed