BDBM50164136 6-(2,6-Dimethyl-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL359898

SMILES Cc1cccc(C)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O

InChI Key InChIKey=YIDJUDDEOGSZCB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164136   

TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50164136(6-(2,6-Dimethyl-phenyl)-8-methyl-2-phenylamino-8H-...)
Affinity DataIC50: 990nMAssay Description:Inhibition of checkpoint kinase Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50164136(6-(2,6-Dimethyl-phenyl)-8-methyl-2-phenylamino-8H-...)
Affinity DataIC50: 990nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164136(6-(2,6-Dimethyl-phenyl)-8-methyl-2-phenylamino-8H-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed