BDBM50164071 (1S,2S)-2-[(Biphenyl-4-ylmethyl)-amino]-cyclopentanecarboxylic acid ([2,2'']bithiophenyl-5-ylmethyl)-amide::CHEMBL360523

SMILES O=C(NCc1ccc(s1)-c1cccs1)[C@H]1CCC[C@@H]1NCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=APNNOVMOGIMLMP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164071   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164071((1S,2S)-2-[(Biphenyl-4-ylmethyl)-amino]-cyclopenta...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164071((1S,2S)-2-[(Biphenyl-4-ylmethyl)-amino]-cyclopenta...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed