BDBM50164046 (1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[([2,2'']bithiophenyl-5-ylmethyl)-amide] 2-[(2''-sulfamoyl-biphenyl-4-ylmethyl)-amide]::CHEMBL368692

SMILES NS(=O)(=O)c1ccccc1-c1ccc(CNC(=O)[C@H]2CCCC[C@@H]2C(=O)NCc2ccc(s2)-c2cccs2)cc1

InChI Key InChIKey=BORBUAZHNAHASZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164046   

TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164046((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[([2,2...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164046((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[([2,2...)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed