BDBM50163926 (E)-N-[(S)-Carbamoyl-(4-chloro-phenyl)-methyl]-N-[(R)-1-(4-chloro-phenyl)-ethyl]-3-phenyl-acrylamide::CHEMBL182051

SMILES C[C@@H](N([C@H](C(N)=O)c1ccc(Cl)cc1)C(=O)\C=C\c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=YGZKZLOWLJRGSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163926   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163926((E)-N-[(S)-Carbamoyl-(4-chloro-phenyl)-methyl]-N-[...)
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity between MDM2 and p53 protein in fluorescence peptide assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed