BDBM50163925 5-{(S)-3-(4-Chloro-phenyl)-4-[(R)-1-(4-chloro-phenyl)-ethyl]-2,5-dioxo-7-phenyl-2,3,4,5-tetrahydro-[1,4]diazepin-1-yl}-pentanoic acid::CHEMBL360540

SMILES C[C@@H](N1[C@@H](c2ccc(Cl)cc2)C(=O)N(CCCCC(O)=O)C(=CC1=O)c1ccccc1)c1ccc(Cl)cc1

InChI Key InChIKey=BHHGNJQROMKDLQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163925   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163925(5-{(S)-3-(4-Chloro-phenyl)-4-[(R)-1-(4-chloro-phen...)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity between MDM2 and p53 protein in fluorescence peptide assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed