BDBM50163913 CHEMBL180777::Tyr-Pro-Phe-Phe-NHNH2

SMILES NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=JZSLBNUKUIAYPN-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50163913   

TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163913(Tyr-Pro-Phe-Phe-NHNH2 | CHEMBL180777)
Affinity DataIC50: 185nMAssay Description:In vitro inhibitory concentration against Opioid receptor delta 1 was measured using mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163913(Tyr-Pro-Phe-Phe-NHNH2 | CHEMBL180777)
Affinity DataIC50: 132nMAssay Description:In vitro inhibitory concentration against Opioid receptor mu 1 was measured using guinea pig ileum assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163913(Tyr-Pro-Phe-Phe-NHNH2 | CHEMBL180777)
Affinity DataIC50: 185nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163913(Tyr-Pro-Phe-Phe-NHNH2 | CHEMBL180777)
Affinity DataIC50: 132nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163913(Tyr-Pro-Phe-Phe-NHNH2 | CHEMBL180777)
Affinity DataKi:  9.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50163913(Tyr-Pro-Phe-Phe-NHNH2 | CHEMBL180777)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed