BDBM50163838 (1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cyclohexyl-1-methyl-ethyl ester::CHEMBL183660::TCMDC-138496

SMILES C[C@@H](CC1CCCCC1)OC(=O)N[C@H]1CCN(C1)C#N

InChI Key InChIKey=GLZGNFOBDIGKFZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50163838   

TargetPro-cathepsin H(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838(TCMDC-138496 | (1-Cyano-pyrrolidin-3-yl)-carbamic ...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory concentration against human cathepsin H using 50 uM L-Arg-beta-naphthalamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838(TCMDC-138496 | (1-Cyano-pyrrolidin-3-yl)-carbamic ...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838(TCMDC-138496 | (1-Cyano-pyrrolidin-3-yl)-carbamic ...)
Affinity DataIC50: 81nMAssay Description:Inhibitory concentration against human cathepsin L using 5 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838(TCMDC-138496 | (1-Cyano-pyrrolidin-3-yl)-carbamic ...)
Affinity DataIC50: 680nMAssay Description:Inhibitory concentration against human cathepsin B using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed