BDBM50163728 (Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-benzyl}-amino)-acetic acid::2-((4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)(benzyl)amino)acetic acid::CHEMBL371120

SMILES Cc1oc(nc1CCOc1ccc(CN(CC(O)=O)Cc2ccccc2)cc1)-c1ccccc1

InChI Key InChIKey=KBXHBLXYBPVCLB-UHFFFAOYSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50163728   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataIC50: 1.77E+3nMAssay Description:Displacement of fluorescein labeled ligand from PPARgamma receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of fluorescein labeled ligand from PPARalpha receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50163728((Benzyl-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-etho...)
Affinity DataEC50:  4.02E+3nMAssay Description:Agonist activity at PPARalpha receptor expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed