BDBM50163567 3-Benzo[1,3]dioxol-5-yl-2-(4-imidazol-1-yl-phenyl)-1,2,3,4-tetrahydro-pyrrolo[3,4-b]quinolin-9-one::CHEMBL177348

SMILES Oc1c2CN(C(c2nc2ccccc12)c1ccc2OCOc2c1)c1ccc(cc1)-n1ccnc1

InChI Key InChIKey=YFLMNOXPPJOBCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50163567   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163567(3-Benzo[1,3]dioxol-5-yl-2-(4-imidazol-1-yl-phenyl)...)
Affinity DataIC50: 1.75nMAssay Description:Inhibitory concentration against phosphodiesterase 5 in rat fetal lung fibroblast (RFL-6) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed