BDBM50163362 CHEMBL3792808

SMILES COC(CN1CCN(CC1)C(=O)Cc1ccc(nc1)-n1cnnn1)c1ccc2C(=O)OCc2c1C

InChI Key InChIKey=ISRDPDAMWUGJKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50163362   

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50163362(CHEMBL3792808)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of rat ROMK expressed in HEK293 cells after 30 mins by [86Rb+] flux functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50163362(CHEMBL3792808)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [35S]-MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed