BDBM50163232 4-(2-Trifluoromethyl-phenyl)-piperazine-1-carboxylic acid isoquinolin-5-ylamide::CHEMBL177219

SMILES FC(F)(F)c1ccccc1N1CCN(CC1)C(=O)Nc1cccc2cnccc12

InChI Key InChIKey=BLRBXYURHNSELP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50163232   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163232(4-(2-Trifluoromethyl-phenyl)-piperazine-1-carboxyl...)
Affinity DataEC50:  7.29E+3nMAssay Description:Effective concentration against rat transient receptor potential vanilloid 1 receptor (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163232(4-(2-Trifluoromethyl-phenyl)-piperazine-1-carboxyl...)
Affinity DataIC50: 2.28E+3nMAssay Description:Inhibition of human transient receptor potential vanilloid 1 receptor (n=4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50163232(4-(2-Trifluoromethyl-phenyl)-piperazine-1-carboxyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat transient receptor potential vanilloid 1 receptor (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed