BDBM50163187 7-Phenyl-1-(5-phenyl-oxazol-2-yl)-heptan-1-one::7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one::CHEMBL173992

SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccccc1

InChI Key InChIKey=GEHXWVPLQWJJQM-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50163187   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataIC50: 80nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataIC50: 700nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataKi:  80nMpH: 9.0Assay Description:Inhibition of FAAH at pH 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataKi:  80nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataKi:  80nMpH: 9.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataKi:  80nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataKi:  80nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50163187(7-phenyl-1-(5-phenyloxazol-2-yl)heptan-1-one | 7-P...)
Affinity DataKi:  140nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed