BDBM50162727 CHEMBL3794524

SMILES c1cc(ccc1C2=C(COCC2)CN3CCN(CC3)c4ccc(cc4)C(=O)NS(=O)(=O)c5ccc(c(c5)[N+](=O)[O-])NC6CCOCC6)Cl

InChI Key InChIKey=AJWKZOOIFOHKSK-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162727   

TargetApoptosis regulator Bcl-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50162727(CHEMBL3794524)
Affinity DataKi:  59nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50162727(CHEMBL3794524)
Affinity DataKi:  5.54E+3nMAssay Description:Binding affinity to Bcl-XL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMed