BDBM50162586 1-Butylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one::CHEMBL178881

SMILES CCCCNn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O

InChI Key InChIKey=MCLUPHLCWVFERX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162586   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162586(1-Butylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-b...)
Affinity DataEC50:  3.48E+3nMAssay Description:Effective concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162586(1-Butylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-b...)
Affinity DataIC50: 951nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1a Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162586(1-Butylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-b...)
Affinity DataIC50: 161nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed