BDBM50162583 1-benzylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one::CHEMBL182191

SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(NCc2ccccc2)c2ccccc12

InChI Key InChIKey=XYWFJCQYELUANV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162583   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162583(1-benzylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-...)
Affinity DataIC50: 129nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162583(1-benzylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-...)
Affinity DataIC50: 5.09E+3nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1a Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162583(1-benzylamino-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-...)
Affinity DataEC50:  1.57E+4nMAssay Description:Effective concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed