BDBM50161991 CHEMBL3792752

SMILES O=C1Cc2cc(ccc2C(=O)N1)-c1ccco1

InChI Key InChIKey=ZNWPCXXFYCAJSS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161991   

TargetTyrosyl-DNA phosphodiesterase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50161991(CHEMBL3792752)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50161991(CHEMBL3792752)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50161991(CHEMBL3792752)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded oligonucleotide DNA containing 3'-phophotyrosine (N14Y) as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50161991(CHEMBL3792752)
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-[32P]-labeled single stranded oligonucleotide DNA containing 3'-phophotyrosine (N14Y) as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed